Programa Científico / Scientific Programme

MIÉRCOLES 20 JUNIO / WEDNESDAY, JUNE 20

09:30 – 10:00 Entrega de documentación / Registration
10:00 – 10:30 Ceremonia de apertura / Opening ceremony
10:30 – 10:45 «Trigésimo Aniversario de la Reunión Científica de la Sociedad Española de Mutagénesis Ambiental (SEMA) 1988–2018«
Eduardo de la Peña (Consejo Superior de Investigaciones Científicas)
Conferencia Inaugural / Opening Conference
10:45 – 11:45 «Plant comet assay in environmental studies: uses, limits and perspectives«
Bertrand Pourrut (Yncrea / ISA Lille / Lille Catholic University)
11:45 – 12:15 Café / Coffee
Sesión I / Session I
Inestabilidad genómica, mutagénesis y carcinogénesis / Genomic instability, mutagenesis and carcinogenesis
Chair: Ricard Marcos (Universitat Autònoma de Barcelona)
12:15 – 12:30 «Follow-up to a positive genotoxicity study result: when science meets regulation criteria. Case study«
David López Ribas (Innoqua Toxicology Consultants, S.L.)
12:30 – 12:45 «FRA-1 and MIR-21 involvement in arsenic-induced cell malignant transformation«
Irene Barguilla (Universitat Autònoma de Barcelona)
12:45 – 13:00 «Set-up of the extraction method for the in vitro genotoxicity evaluation of deep fried meat«
Julen Sanz Serrano (Universidad de Navarra)
13:15 – 15:15 Comida / Lunch
Finocchio Ristorante
Sesión II / Session II
Métodos alternativos a la experimentación animal / Alternative methods to animal testing
Chairs: Eduardo de la Peña (Consejo Superior de Investigaciones Científicas)
Amaya Azqueta (Universidad de Navarra)
15:30 – 15:45 «Future strategies for regulatory genotoxicity assessment«
Guillermo Repetto Kuhn (Universidad Pablo de Olavide / REMA)
15:45 – 16:00 «Generation of «mini-brains» from pluripotent stem cells to study developmental neurotoxicity«
Adela Bernabeu Zornoza (Instituto de Salud Carlos III)
16:00 – 16:15 «New advanced tool for the computational estimation of mutagenesis«
Sergi Gómez (ProtoQSAR, S.L.)
16:15 – 16:30 «Pluripotent stem cells and 3D midbrain organoids as models for Dopaminergic Neurons and the study of environmental toxins associated to Parkinson’s Disease«
Charlotte Palmer (Instituto de Salud Carlos III)
16:30 – 16:45 «Ex vivo genotoxicity testing as an alternative approach to evaluate waterborne contaminants threat – an assay with crayfish gill cells«
Párástu Oskoei (Universidade de Aveiro)
16:45 – 17:00 «Development of a bioassay with Drosophila melanogaster as an alternative model for studying the effect of various pollutants exposure«
Laëtitia Frat (Université Pierre et Marie Curie)
17:00 – 17:30 Café / Coffee
Sesión III / Session III
Epigenética y tecnologías ómicas / Epigenetics and omics technologies
Chairs: Amadeu Creus (Universitat Autònoma de Barcelona)
Óscar Herrero (Universidad Nacional de Educación a Distancia)
17:30 – 17:45 «DNA damage-binding protein 2 (DDB2) plays a key role in DNA methylation dynamics«
Dolores Córdoba Cañero (Universidad de Córdoba)
17:45 – 18:00 «Modification of the epigenome in human cancer cells by expression of a DNA demethylase from plants«
María Victoria García Ortiz (Universidad de Córdoba)
18:00 – 18:15 «Prodiamesa olivacea as a novel non-model organism for ecotoxicity studies in natural scenarios«
Lola Llorente Ortega (Universidad Nacional de Educación a Distancia)
18:15 – 18:30 «Toxic effects of 2-dodecanone in the insect model species Chironomus riparius: potential alternatives of secondary metabolites to synthetic insecticides«
Carmen Pla Bru (Universidad Nacional de Educación a Distancia)
18:30 – 18:45 «Rainbow trout (Oncorhynchus mykiss) hepatocyte 3D-spheroidal aggregates as a valuable tool for studying expression profile after long term exposure: ß-naphthoflavone as a case-study«
Azucena Bermejo Nogales (Instituto Nacional de Investigación y Tecnología Agraria y Alimentaria)
19:30 – 21:00 Visita Guiada / City Tour

JUEVES 21 JUNIO / THURSDAY, JUNE 21

Sesión IV / Session IV
Respuestas genotóxicas: alteraciones fisiológicas y de comportamiento / Genotoxic responses: physiological and behavioural alterations
Chairs: Luisa María Sierra (Universidad de Oviedo)
Rosario Planelló (Universidad Nacional de Educación a Distancia)
10:00 – 10:15 «Ecotoxicological monitoring around a hazardous waste incineration plant situated in a polycontaminated area in North-West Spain, using rodent as sentinels species, and biomarkers«
María Teresa Gómez Mora (Parc Científic de Barcelona)
10:15 – 10:30 «May the contamination history and gender influence the genotoxic responses of the crayfish Procambarus clarkii to the herbicide Viper®?«
Sofia Guilherme (Universidade de Aveiro)
10:30 – 10:45 «DNA of crayfish spermatozoa as a target of waterborne pesticides – an ex vivo screening to predict the impact on progeny fitness«
Raquel Marçal (Universidade de Aveiro)
10:45 – 11:00 «Influence of oncometabolites in the response to DNA damage«
Enol Álvarez González (Universidad de Oviedo)
11:00 – 11:15 «A possible role of the hERG K+ channel on DNA damage response«
Luisa María Sierra Zapico (Universidad de Oviedo)
11:15 – 11:30 «Complex responses in complex scenarios: the use of biomarkers in Chironomus riparius larvae in a polluted river«
María José Servia (Universidade da Coruña)
11:30 – 12:00 Café / Coffee
Conferencia Invitada / Invited Conference
12:00 – 13:00 «Greenhouse effect, chemical contamination of water, and microalgae«
Ángeles Cid (Universidade da Coruña / Centro de Investigacións Científicas Avanzadas)
13:15 – 15:15 Comida / Lunch
Finocchio Ristorante
Sesión V / Session V
Daño, reparación y protección del ADN / DNA damage, repair and protection
Chairs: Adela López de Cerain (Universidad de Navarra)
Antonio Guzmán (Esteve)
15:30 – 15:45 «Radiobiological characterization of primary neuroblastoma cell lines«
Carlos Huertas Castaño (Universidad de Sevilla)
15:45 – 16:00 «Anticancer effects of Olive Leaf Extract (OLE) on lung cell lines A549 and MRC5 and its possible modulating effect on cisplatin toxicity«
Verónica Prados Maniviesa (Universidad de Sevilla)
16:00 – 16:15 «The macroalga Ulva rigida affords genome protection to Drosophila melanogaster via dietary supplementation«
Ana Margarida Marques (Universidade de Aveiro)
16:15 – 16:30 «MTH1 a new anticancer target for neuroblastoma treatment«
Laura Martínez López (Universidad de Sevilla)
16:30 – 17:00 Café / Coffee
Sesión V (continuación) / Session V (continuation)
Daño, reparación y protección del ADN / DNA damage, repair and protection
Chairs: Adela López de Cerain (Universidad de Navarra)
Antonio Guzmán (Esteve)
17:00 – 17:15 «Antigenotoxic and longevity-promoting potential of red seaweeds Porphyra umbilicalis and Grateloupia turuturu in Drosophila melanogaster«
João Ferreira (Universidade de Trás-os-Montes e Alto Douro)
17:15 – 17:30 «The enzyme-modified comet assay: Measuring oxidized and alkylated bases using the 12-gels format«
Damián Muruzábal Gambarte (Universidad de Navarra)
17:30 – 17:45 «DNA damage induced by acute exposures to the plasticizers DEHP, BBP, and DBP, in the model species Chironomus riparius (Diptera)«
Mónica Aquilino Amez (Universidad Nacional de Educación a Distancia)
17:45 – 18:30 Asamblea SEMA / SEMA Assembly
21:30 Cena del Congreso / Congress Dinner
Restaurante Los Arrieros

VIERNES 22 JUNIO / FRIDAY, JUNE 22

Sesión VI / Session VI
Contaminantes emergentes / Emerging pollutants
Chairs: Sofia Guilherme (Universidade de Aveiro)
Paloma Fernández (Universidad Autónoma de Madrid)
10:00 – 10:15 «Effects of Methylmercury on cell death, proliferation and cellular phenotypic specification of human neural stem cells«
Jordi Lli Beltrán (Instituto de Salud Carlos III)
10:15 – 10:30 «Changes in microRNAs expression associated to long-term exposure to nanomaterials«
Sandra Ballesteros (Universitat Autònoma de Barcelona)
10:30 – 10:45 «miR-21 involvement in cobalt and zinc oxide nanoparticles-induced cell malignant transformation«
Adrián Corchero (Universitat Autònoma de Barcelona)
10:45 – 11:00 «Effects of differently shaped TiO2NPs (nano-spheres, nano-rods and nano-wires) on the in vitro model (Caco-2/HT29) of intestinal barrier«
Constanza Cortés (Universitat Autònoma de Barcelona)
11:00 – 11:15 «Effects of graphene oxide and graphene nanoplatelets on the in vitro model of intestinal barrier (Caco2/HT29)«
Josefa Domenech (Universitat Autònoma de Barcelona)
11:15 – 11:30 «Involvement of Mth1 in the toxic and carcinogenic effects of cobalt and zinc oxide nanoparticles«
Alba Hernández (Universitat Autònoma de Barcelona)
11:30 – 11:45 «Time-lapse studies on the effects of silver nanoparticles in the Caco-2/HT29 model of intestinal barrier«
Miriam Sáez (Universitat Autònoma de Barcelona)
11:45 – 12:15 Café / Coffee
Conferencia de Clausura / Closing Conference
12:15 – 13:15 «Impact of pollutants on terrestrial insects: from behaviour disruption to molecular mechanisms«
David Siaussat (Université Pierre et Marie Curie / Institute of Ecology and Environmental Sciences IEES-Paris)
13:15 – 13:45 Ceremonia de clausura / Closing ceremony