Programa Científico / Scientific Programme

MIÉRCOLES 20 JUNIO / WEDNESDAY, JUNE 20

09:30 – 10:00 Entrega de documentación / Registration
10:00 – 10:30 Ceremonia de apertura / Opening ceremony
10:30 – 10:45 Trigésimo Aniversario de la Reunión Científica de la Sociedad Española de Mutagénesis Ambiental (SEMA) 1988–2018
Eduardo de la Peña (Consejo Superior de Investigaciones Científicas)
Conferencia Inaugural / Opening Conference
10:45 – 11:45 Plant comet assay in environmental studies: uses, limits and perspectives
Bertrand Pourrut (Yncrea / ISA Lille / Lille Catholic University)
11:45 – 12:15 Café / Coffee
Sesión I / Session I
Inestabilidad genómica, mutagénesis y carcinogénesis / Genomic instability, mutagenesis and carcinogenesis
Chair: Ricard Marcos (Universitat Autònoma de Barcelona)
12:15 – 12:30 Follow-up to a positive genotoxicity study result: when science meets regulation criteria. Case study
David López Ribas (Innoqua Toxicology Consultants, S.L.)
12:30 – 12:45 FRA-1 and MIR-21 involvement in arsenic-induced cell malignant transformation
Irene Barguilla (Universitat Autònoma de Barcelona)
12:45 – 13:00 Set-up of the extraction method for the in vitro genotoxicity evaluation of deep fried meat
Julen Sanz Serrano (Universidad de Navarra)
13:15 – 15:15 Comida / Lunch
Finocchio Ristorante
Sesión II / Session II
Métodos alternativos a la experimentación animal / Alternative methods to animal testing
Chairs: Eduardo de la Peña (Consejo Superior de Investigaciones Científicas)
Amaya Azqueta (Universidad de Navarra)
15:30 – 15:45 Future strategies for regulatory genotoxicity assessment
Guillermo Repetto Kuhn (Universidad Pablo de Olavide / REMA)
15:45 – 16:00 Generation of “mini-brains” from pluripotent stem cells to study developmental neurotoxicity
Adela Bernabeu Zornoza (Instituto de Salud Carlos III)
16:00 – 16:15 New advanced tool for the computational estimation of mutagenesis
Sergi Gómez (ProtoQSAR, S.L.)
16:15 – 16:30 Pluripotent stem cells and 3D midbrain organoids as models for Dopaminergic Neurons and the study of environmental toxins associated to Parkinson’s Disease
Charlotte Palmer (Instituto de Salud Carlos III)
16:30 – 16:45 Ex vivo genotoxicity testing as an alternative approach to evaluate waterborne contaminants threat – an assay with crayfish gill cells
Párástu Oskoei (Universidade de Aveiro)
16:45 – 17:00 Development of a bioassay with Drosophila melanogaster as an alternative model for studying the effect of various pollutants exposure
Laëtitia Frat (Université Pierre et Marie Curie)
17:00 – 17:30 Café / Coffee
Sesión III / Session III
Epigenética y tecnologías ómicas / Epigenetics and omics technologies
Chairs: Amadeu Creus (Universitat Autònoma de Barcelona)
Óscar Herrero (Universidad Nacional de Educación a Distancia)
17:30 – 17:45 DNA damage-binding protein 2 (DDB2) plays a key role in DNA methylation dynamics
Dolores Córdoba Cañero (Universidad de Córdoba)
17:45 – 18:00 Modification of the epigenome in human cancer cells by expression of a DNA demethylase from plants
María Victoria García Ortiz (Universidad de Córdoba)
18:00 – 18:15 Prodiamesa olivacea as a novel non-model organism for ecotoxicity studies in natural scenarios
Lola Llorente Ortega (Universidad Nacional de Educación a Distancia)
18:15 – 18:30 Toxic effects of 2-dodecanone in the insect model species Chironomus riparius: potential alternatives of secondary metabolites to synthetic insecticides
Carmen Pla Bru (Universidad Nacional de Educación a Distancia)
18:30 – 18:45 Rainbow trout (Oncorhynchus mykiss) hepatocyte 3D-spheroidal aggregates as a valuable tool for studying expression profile after long term exposure: ß-naphthoflavone as a case-study
Azucena Bermejo Nogales (Instituto Nacional de Investigación y Tecnología Agraria y Alimentaria)
19:30 – 21:00 Visita Guiada / City Tour

JUEVES 21 JUNIO / THURSDAY, JUNE 21

Sesión IV / Session IV
Respuestas genotóxicas: alteraciones fisiológicas y de comportamiento / Genotoxic responses: physiological and behavioural alterations
Chairs: Luisa María Sierra (Universidad de Oviedo)
Rosario Planelló (Universidad Nacional de Educación a Distancia)
10:00 – 10:15 Ecotoxicological monitoring around a hazardous waste incineration plant situated in a polycontaminated area in North-West Spain, using rodent as sentinels species, and biomarkers
María Teresa Gómez Mora (Parc Científic de Barcelona)
10:15 – 10:30 May the contamination history and gender influence the genotoxic responses of the crayfish Procambarus clarkii to the herbicide Viper®?
Sofia Guilherme (Universidade de Aveiro)
10:30 – 10:45 DNA of crayfish spermatozoa as a target of waterborne pesticides – an ex vivo screening to predict the impact on progeny fitness
Raquel Marçal (Universidade de Aveiro)
10:45 – 11:00 Influence of oncometabolites in the response to DNA damage
Enol Álvarez González (Universidad de Oviedo)
11:00 – 11:15 A possible role of the hERG K+ channel on DNA damage response
Luisa María Sierra Zapico (Universidad de Oviedo)
11:15 – 11:30 Complex responses in complex scenarios: the use of biomarkers in Chironomus riparius larvae in a polluted river
María José Servia (Universidade da Coruña)
11:30 – 12:00 Café / Coffee
Conferencia Invitada / Invited Conference
12:00 – 13:00 Greenhouse effect, chemical contamination of water, and microalgae
Ángeles Cid (Universidade da Coruña / Centro de Investigacións Científicas Avanzadas)
13:15 – 15:15 Comida / Lunch
Finocchio Ristorante
Sesión V / Session V
Daño, reparación y protección del ADN / DNA damage, repair and protection
Chairs: Adela López de Cerain (Universidad de Navarra)
Antonio Guzmán (Esteve)
15:30 – 15:45 Radiobiological characterization of primary neuroblastoma cell lines
Carlos Huertas Castaño (Universidad de Sevilla)
15:45 – 16:00 Anticancer effects of Olive Leaf Extract (OLE) on lung cell lines A549 and MRC5 and its possible modulating effect on cisplatin toxicity
Verónica Prados Maniviesa (Universidad de Sevilla)
16:00 – 16:15 The macroalga Ulva rigida affords genome protection to Drosophila melanogaster via dietary supplementation
Ana Margarida Marques (Universidade de Aveiro)
16:15 – 16:30 MTH1 a new anticancer target for neuroblastoma treatment
Laura Martínez López (Universidad de Sevilla)
16:30 – 17:00 Café / Coffee
Sesión V (continuación) / Session V (continuation)
Daño, reparación y protección del ADN / DNA damage, repair and protection
Chairs: Adela López de Cerain (Universidad de Navarra)
Antonio Guzmán (Esteve)
17:00 – 17:15 Antigenotoxic and longevity-promoting potential of red seaweeds Porphyra umbilicalis and Grateloupia turuturu in Drosophila melanogaster
João Ferreira (Universidade de Trás-os-Montes e Alto Douro)
17:15 – 17:30 The enzyme-modified comet assay: Measuring oxidized and alkylated bases using the 12-gels format
Damián Muruzábal Gambarte (Universidad de Navarra)
17:30 – 17:45 DNA damage induced by acute exposures to the plasticizers DEHP, BBP, and DBP, in the model species Chironomus riparius (Diptera)
Mónica Aquilino Amez (Universidad Nacional de Educación a Distancia)
17:45 – 18:30 Asamblea SEMA / SEMA Assembly
21:30 Cena del Congreso / Congress Dinner
Restaurante Los Arrieros

VIERNES 22 JUNIO / FRIDAY, JUNE 22

Sesión VI / Session VI
Contaminantes emergentes / Emerging pollutants
Chairs: Sofia Guilherme (Universidade de Aveiro)
Paloma Fernández (Universidad Autónoma de Madrid)
10:00 – 10:15 Effects of Methylmercury on cell death, proliferation and cellular phenotypic specification of human neural stem cells
Jordi Lli Beltrán (Instituto de Salud Carlos III)
10:15 – 10:30 Changes in microRNAs expression associated to long-term exposure to nanomaterials
Sandra Ballesteros (Universitat Autònoma de Barcelona)
10:30 – 10:45 miR-21 involvement in cobalt and zinc oxide nanoparticles-induced cell malignant transformation
Adrián Corchero (Universitat Autònoma de Barcelona)
10:45 – 11:00 Effects of differently shaped TiO2NPs (nano-spheres, nano-rods and nano-wires) on the in vitro model (Caco-2/HT29) of intestinal barrier
Constanza Cortés (Universitat Autònoma de Barcelona)
11:00 – 11:15 Effects of graphene oxide and graphene nanoplatelets on the in vitro model of intestinal barrier (Caco2/HT29)
Josefa Domenech (Universitat Autònoma de Barcelona)
11:15 – 11:30 Involvement of Mth1 in the toxic and carcinogenic effects of cobalt and zinc oxide nanoparticles
Alba Hernández (Universitat Autònoma de Barcelona)
11:30 – 11:45 Time-lapse studies on the effects of silver nanoparticles in the Caco-2/HT29 model of intestinal barrier
Miriam Sáez (Universitat Autònoma de Barcelona)
11:45 – 12:15 Café / Coffee
Conferencia de Clausura / Closing Conference
12:15 – 13:15 Impact of pollutants on terrestrial insects: from behaviour disruption to molecular mechanisms
David Siaussat (Université Pierre et Marie Curie / Institute of Ecology and Environmental Sciences IEES-Paris)
13:15 – 13:45 Ceremonia de clausura / Closing ceremony